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Integrating end-to-end learning with deep geometrical potentials for ab initio RNA structure predict...

Integrating end-to-end learning with deep geometrical potentials for ab initio RNA structure predict...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dfd8edec979243e8aee69699803f3095

Integrating end-to-end learning with deep geometrical potentials for ab initio RNA structure prediction

About this item

Full title

Integrating end-to-end learning with deep geometrical potentials for ab initio RNA structure prediction

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-09, Vol.14 (1), p.5745-13, Article 5745

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

RNAs are fundamental in living cells and perform critical functions determined by their tertiary architectures. However, accurate modeling of 3D RNA structure remains a challenging problem. We present a novel method, DRfold, to predict RNA tertiary structures by simultaneous learning of local frame rotations and geometric restraints from experiment...

Alternative Titles

Full title

Integrating end-to-end learning with deep geometrical potentials for ab initio RNA structure prediction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_dfd8edec979243e8aee69699803f3095

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_dfd8edec979243e8aee69699803f3095

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-41303-9

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