Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amylo...
Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis
About this item
Full title
Author / Creator
Schulte, Tim , Chaves-Sanjuan, Antonio , Speranzini, Valentina , Sicking, Kevin , Milazzo, Melissa , Mazzini, Giulia , Rognoni, Paola , Caminito, Serena , Milani, Paolo , Marabelli, Chiara , Corbelli, Alessandro , Diomede, Luisa , Fiordaliso, Fabio , Anastasia, Luigi , Pappone, Carlo , Merlini, Giampaolo , Bolognesi, Martino , Nuvolone, Mario , Fernández-Busnadiego, Rubén , Palladini, Giovanni and Ricagno, Stefano
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Systemic light chain (LC) amyloidosis (AL) is a disease where organs are damaged by an overload of a misfolded patient-specific antibody-derived LC, secreted by an abnormal B cell clone. The high LC concentration in the blood leads to amyloid deposition at organ sites. Indeed, cryogenic electron microscopy (cryo-EM) has revealed unique amyloid fold...
Alternative Titles
Full title
Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis
Authors, Artists and Contributors
Author / Creator
Chaves-Sanjuan, Antonio
Speranzini, Valentina
Sicking, Kevin
Milazzo, Melissa
Mazzini, Giulia
Rognoni, Paola
Caminito, Serena
Milani, Paolo
Marabelli, Chiara
Corbelli, Alessandro
Diomede, Luisa
Fiordaliso, Fabio
Anastasia, Luigi
Pappone, Carlo
Merlini, Giampaolo
Bolognesi, Martino
Nuvolone, Mario
Fernández-Busnadiego, Rubén
Palladini, Giovanni
Ricagno, Stefano
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e0549faf538c4786ab58772e38f9ac76
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e0549faf538c4786ab58772e38f9ac76
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-50686-2
