Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission
Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission
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Author / Creator
Chang, Xiao L. , Webb, Gabriela M. , Wu, Helen L. , Greene, Justin M. , Abdulhaqq, Shaheed , Bateman, Katherine B. , Reed, Jason S. , Pessoa, Cleiton , Weber, Whitney C. , Maier, Nicholas , Chew, Glen M. , Gilbride, Roxanne M. , Gao, Lina , Agnor, Rebecca , Giobbi, Travis , Torgerson, Jeffrey , Siess, Don , Burnett, Nicole , Fischer, Miranda , Shiel, Oriene , Moats, Cassandra , Patterson, Bruce , Dhody, Kush , Kelly, Scott , Pourhassan, Nader , Magnani, Diogo M. , Smedley, Jeremy , Bimber, Benjamin N. , Haigwood, Nancy L. , Hansen, Scott G. , Brown, Timothy R. , Ndhlovu, Lishomwa C. and Sacha, Jonah B.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
In the absence of a prophylactic vaccine, the use of antiretroviral therapy (ART) as pre-exposure prophylaxis (PrEP) to prevent HIV acquisition by uninfected individuals is a promising approach to slowing the epidemic, but its efficacy is hampered by incomplete patient adherence and ART-resistant variants. Here, we report that competitive inhibitio...
Alternative Titles
Full title
Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission
Authors, Artists and Contributors
Author / Creator
Webb, Gabriela M.
Wu, Helen L.
Greene, Justin M.
Abdulhaqq, Shaheed
Bateman, Katherine B.
Reed, Jason S.
Pessoa, Cleiton
Weber, Whitney C.
Maier, Nicholas
Chew, Glen M.
Gilbride, Roxanne M.
Gao, Lina
Agnor, Rebecca
Giobbi, Travis
Torgerson, Jeffrey
Siess, Don
Burnett, Nicole
Fischer, Miranda
Shiel, Oriene
Moats, Cassandra
Patterson, Bruce
Dhody, Kush
Kelly, Scott
Pourhassan, Nader
Magnani, Diogo M.
Smedley, Jeremy
Bimber, Benjamin N.
Haigwood, Nancy L.
Hansen, Scott G.
Brown, Timothy R.
Ndhlovu, Lishomwa C.
Sacha, Jonah B.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e057d02dc1bf44278b9075dfe29c62e7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e057d02dc1bf44278b9075dfe29c62e7
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-23697-6