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Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission

Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e057d02dc1bf44278b9075dfe29c62e7

Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

In the absence of a prophylactic vaccine, the use of antiretroviral therapy (ART) as pre-exposure prophylaxis (PrEP) to prevent HIV acquisition by uninfected individuals is a promising approach to slowing the epidemic, but its efficacy is hampered by incomplete patient adherence and ART-resistant variants. Here, we report that competitive inhibitio...

Alternative Titles

Full title

Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e057d02dc1bf44278b9075dfe29c62e7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e057d02dc1bf44278b9075dfe29c62e7

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-23697-6

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