Phosphoproteomic profiling of early rheumatoid arthritis synovium reveals active signalling pathways...
Phosphoproteomic profiling of early rheumatoid arthritis synovium reveals active signalling pathways and differentiates inflammatory pathotypes
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Kinases are intracellular signalling mediators and key to sustaining the inflammatory process in rheumatoid arthritis (RA). Oral inhibitors of Janus Kinase family (JAKs) are widely used in RA, while inhibitors of other kinase families e.g. phosphoinositide 3-kinase (PI3K) are under development. Most current biomarker platforms quantify mRNA/protein...
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Phosphoproteomic profiling of early rheumatoid arthritis synovium reveals active signalling pathways and differentiates inflammatory pathotypes
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TN_cdi_doaj_primary_oai_doaj_org_article_e05818fb70ad4c61af8d63ded8c3f639
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e05818fb70ad4c61af8d63ded8c3f639
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ISSN
1478-6362,1478-6354
E-ISSN
1478-6362
DOI
10.1186/s13075-024-03351-4
