A Mouse Model of Beta-Cell Dysfunction as Seen in Human Type 2 Diabetes
A Mouse Model of Beta-Cell Dysfunction as Seen in Human Type 2 Diabetes
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Publisher
Cairo, Egypt: Hindawi Publishing Corporation
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Language
English
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Publisher
Cairo, Egypt: Hindawi Publishing Corporation
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Contents
Loss of first-phase insulin release is an early pathogenic feature of type 2 diabetes (T2D). Various mouse models exist to study T2D; however, few recapitulate the early β-cell defects seen in humans. We sought to develop a nongenetic mouse model of T2D that exhibits reduced first-phase insulin secretion without a significant deficit in pancreatic...
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Full title
A Mouse Model of Beta-Cell Dysfunction as Seen in Human Type 2 Diabetes
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TN_cdi_doaj_primary_oai_doaj_org_article_e09a644f4b1642b5a3e19ab50e3c96d0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e09a644f4b1642b5a3e19ab50e3c96d0
Other Identifiers
ISSN
2314-6745
E-ISSN
2314-6753
DOI
10.1155/2018/6106051
