ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens
ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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T cell dependent secretory IgA (SIgA) generated in the Peyer’s patches (PPs) of the small intestine shapes a broadly diverse microbiota that is crucial for host physiology. The mutualistic co-evolution of host and microbes led to the relative tolerance of host’s immune system towards commensal microorganisms. The ATP-gated ionotropic P2X7 receptor...
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Full title
ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens
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TN_cdi_doaj_primary_oai_doaj_org_article_e0e24831b05347f7a1b912b1db0a67fd
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e0e24831b05347f7a1b912b1db0a67fd
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-08156-z
