Cytoskeletal disarray increases arrhythmogenic vulnerability during sympathetic stimulation in a mod...
Cytoskeletal disarray increases arrhythmogenic vulnerability during sympathetic stimulation in a model of hypertrophic cardiomyopathy
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Familial hypertrophic cardiomyopathy (FHC) patients are advised to avoid strenuous exercise due to increased risk of arrhythmias. Mice expressing the human FHC-causing mutation R403Q in the myosin heavy chain gene (
MYH6
) recapitulate the human phenotype, including cytoskeletal disarray and increased arrhythmia susceptibility. Following in v...
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Full title
Cytoskeletal disarray increases arrhythmogenic vulnerability during sympathetic stimulation in a model of hypertrophic cardiomyopathy
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TN_cdi_doaj_primary_oai_doaj_org_article_e1010dcf8ddf4f0397cc92001ff5aa96
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e1010dcf8ddf4f0397cc92001ff5aa96
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-38296-2
