Neutralizing IFNγ improves safety without compromising efficacy of CAR-T cell therapy in B-cell mali...
Neutralizing IFNγ improves safety without compromising efficacy of CAR-T cell therapy in B-cell malignancies
About this item
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Author / Creator
Manni, Simona , Del Bufalo, Francesca , Merli, Pietro , Silvestris, Domenico Alessandro , Guercio, Marika , Caruso, Simona , Reddel, Sofia , Iaffaldano, Laura , Pezzella, Michele , Di Cecca, Stefano , Sinibaldi, Matilde , Ottaviani, Alessio , Quadraccia, Maria Cecilia , Aurigemma, Mariasole , Sarcinelli, Andrea , Ciccone, Roselia , Abbaszadeh, Zeinab , Ceccarelli, Manuela , De Vito, Rita , Lodi, Maria Chiara , Cefalo, Maria Giuseppina , Mastronuzzi, Angela , De Angelis, Biagio , Locatelli, Franco and Quintarelli, Concetta
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Chimeric antigen receptor T (CAR-T) cell therapy may achieve long-lasting remission in patients with B-cell malignancies not responding to conventional therapies. However, potentially severe and hard-to-manage side effects, including cytokine release syndrome (CRS), neurotoxicity and macrophage activation syndrome, and the lack of pathophysiologica...
Alternative Titles
Full title
Neutralizing IFNγ improves safety without compromising efficacy of CAR-T cell therapy in B-cell malignancies
Authors, Artists and Contributors
Author / Creator
Del Bufalo, Francesca
Merli, Pietro
Silvestris, Domenico Alessandro
Guercio, Marika
Caruso, Simona
Reddel, Sofia
Iaffaldano, Laura
Pezzella, Michele
Di Cecca, Stefano
Sinibaldi, Matilde
Ottaviani, Alessio
Quadraccia, Maria Cecilia
Aurigemma, Mariasole
Sarcinelli, Andrea
Ciccone, Roselia
Abbaszadeh, Zeinab
Ceccarelli, Manuela
De Vito, Rita
Lodi, Maria Chiara
Cefalo, Maria Giuseppina
Mastronuzzi, Angela
De Angelis, Biagio
Locatelli, Franco
Quintarelli, Concetta
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e13fedf5b3e94ec1a443079d5e0501e7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e13fedf5b3e94ec1a443079d5e0501e7
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-38723-y
