Elevated microglial oxidative phosphorylation and phagocytosis stimulate post-stroke brain remodelin...
Elevated microglial oxidative phosphorylation and phagocytosis stimulate post-stroke brain remodeling and cognitive function recovery in mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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New research shows that disease-associated microglia in neurodegenerative brains present features of elevated phagocytosis, lysosomal functions, and lipid metabolism, which benefit brain repair. The underlying mechanisms remain poorly understood. Intracellular pH (pH
i
) is important for regulating aerobic glycolysis in microglia, where Na/H...
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Elevated microglial oxidative phosphorylation and phagocytosis stimulate post-stroke brain remodeling and cognitive function recovery in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_e142eac368b54c4dbc767ae2fa4d5e53
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e142eac368b54c4dbc767ae2fa4d5e53
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-021-02984-4
