Nonstimulatory peptide–MHC enhances human T-cell antigen-specific responses by amplifying proximal T...
Nonstimulatory peptide–MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Foreign antigens are presented by antigen-presenting cells in the presence of abundant endogenous peptides that are nonstimulatory to the T cell. In mouse T cells, endogenous, nonstimulatory peptides have been shown to enhance responses to specific peptide antigens, a phenomenon termed coagonism. However, whether coagonism also occurs in human T ce...
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Full title
Nonstimulatory peptide–MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling
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TN_cdi_doaj_primary_oai_doaj_org_article_e1513454279048d48870135ba8d4a18d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e1513454279048d48870135ba8d4a18d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-05288-0
