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Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surve...

Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surve...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e1ccfb7e084e42f698fa39ef31fcea3d

Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance

About this item

Full title

Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-03, Vol.8 (1), p.14760-14760, Article 14760

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

γδ T cells are considered to be innate-like lymphocytes that respond rapidly to stress without clonal selection and differentiation. Here we use next-generation sequencing to probe how this paradigm relates to human Vδ2
neg
T cells, implicated in responses to viral infection and cancer. The prevalent Vδ1 T cell receptor (TCR) repertoire is pr...

Alternative Titles

Full title

Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e1ccfb7e084e42f698fa39ef31fcea3d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e1ccfb7e084e42f698fa39ef31fcea3d

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms14760

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