Pan-cancer deconvolution of tumour composition using DNA methylation
Pan-cancer deconvolution of tumour composition using DNA methylation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The nature and extent of immune cell infiltration into solid tumours are key determinants of therapeutic response. Here, using a DNA methylation-based approach to tumour cell fraction deconvolution, we report the integrated analysis of tumour composition and genomics across a wide spectrum of solid cancers. Initially studying head and neck squamous...
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Pan-cancer deconvolution of tumour composition using DNA methylation
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TN_cdi_doaj_primary_oai_doaj_org_article_e1cf9d7772ff44b4a8372f27b4755fbd
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e1cf9d7772ff44b4a8372f27b4755fbd
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-05570-1