Umbilical cord-derived mesenchymal stromal cells immunomodulate and restore actin dynamics and phago...
Umbilical cord-derived mesenchymal stromal cells immunomodulate and restore actin dynamics and phagocytosis of LPS-activated microglia via PI3K/Akt/Rho GTPase pathway
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Microglia are the immune cells in the central nervous system surveying environment and reacting to various injuries. Activated microglia may cause impaired synaptic plasticity, therefore modulating and restoring them to neutral phenotype is crucial to counteract a pro-inflammatory, neurotoxic state. In this study, we focused on elucidating whether...
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Umbilical cord-derived mesenchymal stromal cells immunomodulate and restore actin dynamics and phagocytosis of LPS-activated microglia via PI3K/Akt/Rho GTPase pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_e1f8f002aeb345da9196671231da750e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e1f8f002aeb345da9196671231da750e
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ISSN
2058-7716
E-ISSN
2058-7716
DOI
10.1038/s41420-021-00436-w
