Granzyme B inhibition reduces disease severity in autoimmune blistering diseases
Granzyme B inhibition reduces disease severity in autoimmune blistering diseases
About this item
Full title
Author / Creator
Hiroyasu, Sho , Zeglinski, Matthew R. , Zhao, Hongyan , Pawluk, Megan A. , Turner, Christopher T. , Kasprick, Anika , Tateishi, Chiharu , Nishie, Wataru , Burleigh, Angela , Lennox, Peter A. , Van Laeken, Nancy , Carr, Nick J. , Petersen, Frank , Crawford, Richard I. , Shimizu, Hiroshi , Tsuruta, Daisuke , Ludwig, Ralf J. and Granville, David J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Pemphigoid diseases refer to a group of severe autoimmune skin blistering diseases characterized by subepidermal blistering and loss of dermal-epidermal adhesion induced by autoantibody and immune cell infiltrate at the dermal-epidermal junction and upper dermis. Here, we explore the role of the immune cell-secreted serine protease, granzyme B, in...
Alternative Titles
Full title
Granzyme B inhibition reduces disease severity in autoimmune blistering diseases
Authors, Artists and Contributors
Author / Creator
Zeglinski, Matthew R.
Zhao, Hongyan
Pawluk, Megan A.
Turner, Christopher T.
Kasprick, Anika
Tateishi, Chiharu
Nishie, Wataru
Burleigh, Angela
Lennox, Peter A.
Van Laeken, Nancy
Carr, Nick J.
Petersen, Frank
Crawford, Richard I.
Shimizu, Hiroshi
Tsuruta, Daisuke
Ludwig, Ralf J.
Granville, David J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e1fcb0e4655740288ff9814e14e03085
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e1fcb0e4655740288ff9814e14e03085
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20604-3
