Glycosylated nanoparticle-based PfCSP vaccine confers long-lasting antibody responses and sterile pr...
Glycosylated nanoparticle-based PfCSP vaccine confers long-lasting antibody responses and sterile protection in mouse malaria model
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Author / Creator
Ludwig, Julia , Scally, Stephen W. , Costa, Giulia , Hoffmann, Sandro , Murugan, Rajagopal , Lossin, Jana , Prieto, Katherine , Obraztsova, Anna , Lobeto, Nina , Franke-Fayard, Blandine , Janse, Chris J. , Lebas, Celia , Collin, Nicolas , Binter, Spela , Kellam, Paul , Levashina, Elena A. , Wardemann, Hedda and Julien, Jean-Philippe
Publisher
London: Nature Publishing Group UK
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Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The development of an effective and durable vaccine remains a central goal in the fight against malaria. Circumsporozoite protein (CSP) is the major surface protein of sporozoites and the target of the only licensed
Plasmodium falciparum
(Pf) malaria vaccine, RTS,S/AS01. However, vaccine efficacy is low and short-lived, highlighting the need...
Alternative Titles
Full title
Glycosylated nanoparticle-based PfCSP vaccine confers long-lasting antibody responses and sterile protection in mouse malaria model
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e21e8d2652bd4aaba4120441ac9e5abb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e21e8d2652bd4aaba4120441ac9e5abb
Other Identifiers
ISSN
2059-0105
E-ISSN
2059-0105
DOI
10.1038/s41541-023-00653-7