Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-...
Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes
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Author / Creator
Ledsgaard, Line , Wade, Jack , Jenkins, Timothy P. , Boddum, Kim , Oganesyan, Irina , Harrison, Julian A. , Villar, Pedro , Leah, Rachael A. , Zenobi, Renato , Schoffelen, Sanne , Voldborg, Bjørn , Ljungars, Anne , McCafferty, John , Lomonte, Bruno , Gutiérrez, José M. , Laustsen, Andreas H. and Karatt-Vellatt, Aneesh
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Snakebite envenoming continues to claim many lives across the globe, necessitating the development of improved therapies. To this end, broadly-neutralizing human monoclonal antibodies may possess advantages over current plasma-derived antivenoms by offering superior safety and high neutralization capacity. Here, we report the establishment of a pip...
Alternative Titles
Full title
Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e25513bb2bca42949088d83d90b24bca
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e25513bb2bca42949088d83d90b24bca
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-36393-4
