Sortilin drives hypertension by modulating sphingolipid/ceramide homeostasis and by triggering oxida...
Sortilin drives hypertension by modulating sphingolipid/ceramide homeostasis and by triggering oxidative stress
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United States: American Society for Clinical Investigation
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English
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United States: American Society for Clinical Investigation
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Sortilin is a glycoprotein mainly known for its role as a trafficking molecule directing proteins to specific secretory or endocytic compartments of the cell. Its actual contribution to essential hypertension has remained hitherto elusive. Combining top-notch in vivo, ex vivo, and in vitro approaches to clinical investigations, Di Pietro et al. exp...
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Sortilin drives hypertension by modulating sphingolipid/ceramide homeostasis and by triggering oxidative stress
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TN_cdi_doaj_primary_oai_doaj_org_article_e27f62e6197c40aa85d141515ccd4c84
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e27f62e6197c40aa85d141515ccd4c84
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ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI156624
