A novel mutation of SATB2 inhibits odontogenesis of human dental pulp stem cells through Wnt/β-caten...
A novel mutation of SATB2 inhibits odontogenesis of human dental pulp stem cells through Wnt/β-catenin signaling pathway
About this item
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Author / Creator
Xin, Tianyi , Li, Qian , Bai, Rushui , Zhang, Ting , Zhou, Yanheng , Zhang, Yuehua , Han, Bing and Yang, Ruili
Publisher
England: BioMed Central
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central
Subjects
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Scope and Contents
Contents
SATB2-associated syndrome (SAS) is a multisystem disorder caused by mutation of human SATB2 gene. Tooth agenesis is one of the most common phenotypes observed in SAS. Our study aimed at identifying novel variant of SATB2 in a patient with SAS, and to investigate the cellular and molecular mechanism of tooth agenesis caused by SATB2 mutation.
We...
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Full title
A novel mutation of SATB2 inhibits odontogenesis of human dental pulp stem cells through Wnt/β-catenin signaling pathway
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e29a3f12811a412799274e14e498f664
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e29a3f12811a412799274e14e498f664
Other Identifiers
ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/s13287-021-02660-8
