A concise and scalable chemoenzymatic synthesis of prostaglandins
A concise and scalable chemoenzymatic synthesis of prostaglandins
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Author / Creator
Yin, Yunpeng , Wang, Jinxin and Li, Jian
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Prostaglandins have garnered significant attention from synthetic chemists due to their exceptional biological activities. In this report, we present a concise chemoenzymatic synthesis method for several representative prostaglandins, achieved in 5 to 7 steps. Notably, the common intermediate bromohydrin, a radical equivalent of Corey lactone, is c...
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Full title
A concise and scalable chemoenzymatic synthesis of prostaglandins
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TN_cdi_doaj_primary_oai_doaj_org_article_e2cad25c3749465fb3514f8d5acac5e6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e2cad25c3749465fb3514f8d5acac5e6
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-46960-y
