Tumor microenvironment remodeling with a telomere-targeting agent and its cooperative antitumor effe...
Tumor microenvironment remodeling with a telomere-targeting agent and its cooperative antitumor effects with a nanovaccine
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Author / Creator
Bai, Jing , Wang, Mengzhen , Luo, Yiming , Duan, Biao , Yang, Ying , Fu, Yuting , Li, Shuqin , Yang, Zhongqian , Zheng, Peng , Yu, Tong , Yin, Xin , Bai, Hongmei , Long, Qiong and Ma, Yanbing
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
The nucleoside analogue 6-thio-2'-deoxyguanosine (6-thio-dG, also known as THIO) is a telomere-targeting agent with important clinical potency. It can selectively kill telomerase-positive tumor cells. We previously reported that THIO could successfully induce immunogenic cell death (ICD) in multiple mouse tumor cell lines. In this study, we further...
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Full title
Tumor microenvironment remodeling with a telomere-targeting agent and its cooperative antitumor effects with a nanovaccine
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TN_cdi_doaj_primary_oai_doaj_org_article_e2d1eaca086a42e8bb1c1b6bfa01244f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e2d1eaca086a42e8bb1c1b6bfa01244f
Other Identifiers
ISSN
1477-3155
E-ISSN
1477-3155
DOI
10.1186/s12951-025-03471-2
