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Antiviral immunity within neural stem cells distinguishes Enterovirus-D68 strain differences in fore...

Antiviral immunity within neural stem cells distinguishes Enterovirus-D68 strain differences in fore...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e300f8d4ec874862bf49f7c9afbf789c

Antiviral immunity within neural stem cells distinguishes Enterovirus-D68 strain differences in forebrain organoids

About this item

Full title

Antiviral immunity within neural stem cells distinguishes Enterovirus-D68 strain differences in forebrain organoids

Publisher

England: BioMed Central Ltd

Journal title

Journal of neuroinflammation, 2024-11, Vol.21 (1), p.288-17, Article 288

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Neural stem cells have intact innate immune responses that protect them from virus infection and cell death. Yet, viruses can antagonize such responses to establish neuropathogenesis. Using a forebrain organoid model system at two developmental time points, we identified that neural stem cells, in particular radial glia, are basally primed to respo...

Alternative Titles

Full title

Antiviral immunity within neural stem cells distinguishes Enterovirus-D68 strain differences in forebrain organoids

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e300f8d4ec874862bf49f7c9afbf789c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e300f8d4ec874862bf49f7c9afbf789c

Other Identifiers

ISSN

1742-2094

E-ISSN

1742-2094

DOI

10.1186/s12974-024-03275-5

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