Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopo...
Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Fusion genes are hallmarks of various cancer types and important determinants for diagnosis, prognosis and treatment. Fusion gene partner choice and breakpoint-position promiscuity restricts diagnostic detection, even for known and recurrent configurations. Here, we develop FUDGE (FUsion Detection from Gene Enrichment) to accurately and impartially...
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Full title
Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing
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TN_cdi_doaj_primary_oai_doaj_org_article_e33d69e505f647c4a248cf888947cfbb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e33d69e505f647c4a248cf888947cfbb
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-16641-7
