Differences in molecular phenotype in mouse and human hypertrophic cardiomyopathy
Differences in molecular phenotype in mouse and human hypertrophic cardiomyopathy
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Hypertrophic cardiomyopathy (HCM) is characterized by phenotypic heterogeneity. We investigated the molecular basis of the cardiac phenotype in two mouse models at established disease stage (mouse-HCM), and human myectomy tissue (human-HCM). We analyzed the transcriptome in 2 mouse models with non-obstructive HCM (R403Q-MyHC, R92W-TnT)/littermate-c...
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Differences in molecular phenotype in mouse and human hypertrophic cardiomyopathy
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TN_cdi_doaj_primary_oai_doaj_org_article_e365172126d5471c8bde7c2cc906f5f3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e365172126d5471c8bde7c2cc906f5f3
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-89451-6
