Exploring the impact of APOE ɛ4 on functional connectivity in Alzheimer’s disease across cognitive i...
Exploring the impact of APOE ɛ4 on functional connectivity in Alzheimer’s disease across cognitive impairment levels
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Alzheimer’s Disease Neuroimaging Initiative , Dong, Kangli , Liang, Wei , Hou, Ting , Lu, Zhijie , Hao, Yixuan , Li, Chenrui , Qiu, Yue , Kong, Nan , Cheng, Yan , Wen, Yaqi , Ma, Wanyin , Zheng, Wenbin , Guan, Jitian , Lin, Yan , Huang, Kai , Zhang, Lu , Chen, Siya , Ma, Xiangyuan , Wu, Renhua and Wei, Naili
Publisher
United States: Elsevier Inc
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English
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United States: Elsevier Inc
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The apolipoprotein E (APOE) ɛ4 allele is a recognized genetic risk factor for Alzheimer’s Disease (AD). Studies have shown that APOE ɛ4 mediates the modulation of intrinsic functional brain networks in cognitively normal individuals and significantly disrupts the whole-brain topological structure in AD patients. However, how APOE ɛ4 regulates brain...
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Exploring the impact of APOE ɛ4 on functional connectivity in Alzheimer’s disease across cognitive impairment levels
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TN_cdi_doaj_primary_oai_doaj_org_article_e3657f71f7674559b8d5d9cd75df37b4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e3657f71f7674559b8d5d9cd75df37b4
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ISSN
1053-8119,1095-9572
E-ISSN
1095-9572
DOI
10.1016/j.neuroimage.2024.120951