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Exploring the impact of APOE ɛ4 on functional connectivity in Alzheimer’s disease across cognitive i...

Exploring the impact of APOE ɛ4 on functional connectivity in Alzheimer’s disease across cognitive i...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e3657f71f7674559b8d5d9cd75df37b4

Exploring the impact of APOE ɛ4 on functional connectivity in Alzheimer’s disease across cognitive impairment levels

About this item

Full title

Exploring the impact of APOE ɛ4 on functional connectivity in Alzheimer’s disease across cognitive impairment levels

Publisher

United States: Elsevier Inc

Journal title

NeuroImage (Orlando, Fla.), 2025-01, Vol.305, p.120951, Article 120951

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

The apolipoprotein E (APOE) ɛ4 allele is a recognized genetic risk factor for Alzheimer’s Disease (AD). Studies have shown that APOE ɛ4 mediates the modulation of intrinsic functional brain networks in cognitively normal individuals and significantly disrupts the whole-brain topological structure in AD patients. However, how APOE ɛ4 regulates brain...

Alternative Titles

Full title

Exploring the impact of APOE ɛ4 on functional connectivity in Alzheimer’s disease across cognitive impairment levels

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e3657f71f7674559b8d5d9cd75df37b4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e3657f71f7674559b8d5d9cd75df37b4

Other Identifiers

ISSN

1053-8119,1095-9572

E-ISSN

1095-9572

DOI

10.1016/j.neuroimage.2024.120951

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