Dimethylfumarate inhibits microglial and astrocytic inflammation by suppressing the synthesis of nit...
Dimethylfumarate inhibits microglial and astrocytic inflammation by suppressing the synthesis of nitric oxide, IL-1β, TNF-α and IL-6 in an in-vitro model of brain inflammation
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BioMed Central Ltd
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Language
English
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BioMed Central Ltd
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Contents
Brain inflammation plays a central role in multiple sclerosis (MS). Dimethylfumarate (DMF), the main ingredient of an oral formulation of fumaric acid esters with proven therapeutic efficacy in psoriasis, has recently been found to ameliorate the course of relapsing-remitting MS. Glial cells are the effector cells of neuroinflammation; however, lit...
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Full title
Dimethylfumarate inhibits microglial and astrocytic inflammation by suppressing the synthesis of nitric oxide, IL-1β, TNF-α and IL-6 in an in-vitro model of brain inflammation
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TN_cdi_doaj_primary_oai_doaj_org_article_e366291f1c704fec8649e0f20ff94ed9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e366291f1c704fec8649e0f20ff94ed9
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/1742-2094-7-30
