GATA3 induces mitochondrial biogenesis in primary human CD4+ T cells during DNA damage
GATA3 induces mitochondrial biogenesis in primary human CD4+ T cells during DNA damage
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
GATA3 is as a lineage-specific transcription factor that drives the differentiation of CD4
+
T helper 2 (Th2) cells, but is also involved in a variety of processes such as immune regulation, proliferation and maintenance in other T cell and non-T cell lineages. Here we show a mechanism utilised by CD4
+
T cells to increase mitochondrial...
Alternative Titles
Full title
GATA3 induces mitochondrial biogenesis in primary human CD4+ T cells during DNA damage
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TN_cdi_doaj_primary_oai_doaj_org_article_e3707e322df34c44b2251936c03964a1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e3707e322df34c44b2251936c03964a1
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-23715-7
