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Retinal prolactin isoform PRLΔE1 sustains rod disease in inherited retinal degenerations

Retinal prolactin isoform PRLΔE1 sustains rod disease in inherited retinal degenerations

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e37984bba17c4ae580d9b5b917c7b0d9

Retinal prolactin isoform PRLΔE1 sustains rod disease in inherited retinal degenerations

About this item

Full title

Retinal prolactin isoform PRLΔE1 sustains rod disease in inherited retinal degenerations

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2024-09, Vol.15 (9), p.682-10, Article 682

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

PRLΔE1
, a retina-specific isoform of prolactin, is expressed in multiple and diverse forms of canine inherited retinal degeneration (IRD). We find that while
PRLΔE1
expression in rods is not associated with the initial phase of disease characterized by acute photoreceptor cell death, it is associated with the protracted phase of slow cell...

Alternative Titles

Full title

Retinal prolactin isoform PRLΔE1 sustains rod disease in inherited retinal degenerations

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e37984bba17c4ae580d9b5b917c7b0d9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e37984bba17c4ae580d9b5b917c7b0d9

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-024-07070-1

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