Identification of residues critical for the extension of Munc18-1 domain 3a
Identification of residues critical for the extension of Munc18-1 domain 3a
About this item
Full title
Author / Creator
Wang, Xianping , Gong, Jihong , Zhu, Le , Chen, Huidan , Jin, Ziqi , Mo, Xiaoqiang , Wang, Shen , Yang, Xiaofei and Ma, Cong
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Neurotransmitter release depends on the fusion of synaptic vesicles with the presynaptic membrane and is mainly mediated by SNARE complex assembly. During the transition of Munc18-1/Syntaxin-1 to the SNARE complex, the opening of the Syntaxin-1 linker region catalyzed by Munc13-1 leads to the extension of the domain 3a hinge loop, which enables dom...
Alternative Titles
Full title
Identification of residues critical for the extension of Munc18-1 domain 3a
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e3818499f5ad4871b471f3bafec2dd97
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e3818499f5ad4871b471f3bafec2dd97
Other Identifiers
ISSN
1741-7007
E-ISSN
1741-7007
DOI
10.1186/s12915-023-01655-6
