Application of Highly Immunocompromised Mice for the Establishment of Patient-Derived Xenograft (PDX...
Application of Highly Immunocompromised Mice for the Establishment of Patient-Derived Xenograft (PDX) Models
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Patient-derived xenograft (PDX) models are created by engraftment of patient tumor tissues into immunocompetent mice. Since a PDX model retains the characteristics of the primary patient tumor including gene expression profiles and drug responses, it has become the most reliable in vivo human cancer model. The engraftment rate increases with the in...
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Application of Highly Immunocompromised Mice for the Establishment of Patient-Derived Xenograft (PDX) Models
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TN_cdi_doaj_primary_oai_doaj_org_article_e39d3f3e92fc401ca8ae30c20c6880c8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e39d3f3e92fc401ca8ae30c20c6880c8
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells8080889
