The roles of KRAS in cancer metabolism, tumor microenvironment and clinical therapy
The roles of KRAS in cancer metabolism, tumor microenvironment and clinical therapy
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
KRAS is one of the most mutated genes, driving alternations in metabolic pathways that include enhanced nutrient uptaking, increased glycolysis, elevated glutaminolysis, and heightened synthesis of fatty acids and nucleotides. However, the beyond mechanisms of KRAS-modulated cancer metabolisms remain incompletely understood. In this review, we aim...
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Full title
The roles of KRAS in cancer metabolism, tumor microenvironment and clinical therapy
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TN_cdi_doaj_primary_oai_doaj_org_article_e39ea3a6a77440c1b3384cca04f51b10
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e39ea3a6a77440c1b3384cca04f51b10
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-024-02218-1
