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Evaluating and mitigating clinical samples matrix effects on TX-TL cell-free performance

Evaluating and mitigating clinical samples matrix effects on TX-TL cell-free performance

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e3ba46406fac4d0697f85f0bef7a6592

Evaluating and mitigating clinical samples matrix effects on TX-TL cell-free performance

About this item

Full title

Evaluating and mitigating clinical samples matrix effects on TX-TL cell-free performance

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-08, Vol.12 (1), p.13785-13785, Article 13785

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cell-free biosensors are promising tools for medical diagnostics, yet their performance can be affected by matrix effects arising from the sample itself or from external components. Here we systematically evaluate the performance and robustness of cell-free systems in serum, plasma, urine, and saliva using two reporter systems, sfGFP and luciferase...

Alternative Titles

Full title

Evaluating and mitigating clinical samples matrix effects on TX-TL cell-free performance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e3ba46406fac4d0697f85f0bef7a6592

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e3ba46406fac4d0697f85f0bef7a6592

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-17583-4

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