T cells specific for post-translational modifications escape intrathymic tolerance induction
T cells specific for post-translational modifications escape intrathymic tolerance induction
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Establishing effective central tolerance requires the promiscuous expression of tissue-restricted antigens by medullary thymic epithelial cells. However, whether central tolerance also extends to post-translationally modified proteins is not clear. Here we show a mouse model of autoimmunity in which disease development is dependent on post-translat...
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T cells specific for post-translational modifications escape intrathymic tolerance induction
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TN_cdi_doaj_primary_oai_doaj_org_article_e3bc31ec183743a0819cb2d858e9e59c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e3bc31ec183743a0819cb2d858e9e59c
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-02763-y
