Unifying Hypothesis of Dopamine Neuron Loss in Neurodegenerative Diseases: Focusing on Alzheimer's D...
Unifying Hypothesis of Dopamine Neuron Loss in Neurodegenerative Diseases: Focusing on Alzheimer's Disease
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Switzerland: Frontiers Research Foundation
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English
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Switzerland: Frontiers Research Foundation
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Early-onset AD is strongly linked to autosomal dominant mutations in amyloid precursor protein (APP) and presenilin genes [PSEN1, PSEN2; (Blennow et al., 2006)] while the most common genetic variant for late-onset AD is apolipoprotein E (APOE), a three-allele polymorphism (ε2, ε3, and ε4) where ε4 is the high-risk allele (Corder et al., 1993). [......
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Unifying Hypothesis of Dopamine Neuron Loss in Neurodegenerative Diseases: Focusing on Alzheimer's Disease
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TN_cdi_doaj_primary_oai_doaj_org_article_e3be52f49047479f9aaca8c1ce809a05
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e3be52f49047479f9aaca8c1ce809a05
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ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2019.00123
