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Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase

Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e3bf6cdb8c36482bbd4222776e21ef8f

Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase

About this item

Full title

Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-07, Vol.7 (1), p.6329-10, Article 6329

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Intestinal epithelial barrier properties are maintained by a junctional complex consisting of tight junctions (TJ), adherens junctions (AJ) and desmosomes. Desmoglein 2 (Dsg2), an adhesion molecule of desmosomes and the only Dsg isoform expressed in enterocytes, is required for epithelial barrier properties and may contribute to barrier defects in...

Alternative Titles

Full title

Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e3bf6cdb8c36482bbd4222776e21ef8f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e3bf6cdb8c36482bbd4222776e21ef8f

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-06713-y

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