N 6 -methyladenosine RNA modification suppresses antiviral innate sensing pathways via reshaping dou...
N 6 -methyladenosine RNA modification suppresses antiviral innate sensing pathways via reshaping double-stranded RNA
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Author / Creator
Qiu, Weinan , Zhang, Qingyang , Zhang, Rui , Lu, Yangxu , Wang, Xin , Tian, Huabin , Yang, Ying , Gu, Zijuan , Gao, Yanan , Yang, Xin , Cui, Guanshen , Sun, Baofa , Peng, Yanan , Deng, Hongyu , Peng, Hua , Yang, Angang , Yang, Yun-Gui and Yang, Pengyuan
Publisher
England: Nature Portfolio
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Language
English
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Publisher
England: Nature Portfolio
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Contents
Double-stranded RNA (dsRNA) is a virus-encoded signature capable of triggering intracellular Rig-like receptors (RLR) to activate antiviral signaling, but whether intercellular dsRNA structural reshaping mediated by the N
-methyladenosine (m
A) modification modulates this process remains largely unknown. Here, we show that, in response to inf...
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Full title
N 6 -methyladenosine RNA modification suppresses antiviral innate sensing pathways via reshaping double-stranded RNA
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TN_cdi_doaj_primary_oai_doaj_org_article_e3ca47ef6654412d86d5ab34d1d96bcf
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e3ca47ef6654412d86d5ab34d1d96bcf
Other Identifiers
E-ISSN
2041-1723
DOI
10.1038/s41467-021-21904-y
