Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation
Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation
About this item
Full title
Author / Creator
Lang, Tali , Lee, Jacinta P. W. , Elgass, Kirstin , Pinar, Anita A. , Tate, Michelle D. , Aitken, Elizabeth H. , Fan, Huapeng , Creed, Sarah J. , Deen, Nadia S. , Traore, Daouda A. K. , Mueller, Ivo , Stanisic, Danielle , Baiwog, Francesca S. , Skene, Colin , Wilce, Matthew C. J. , Mansell, Ashley , Morand, Eric F. and Harris, James
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Macrophage migration inhibitory factor (MIF) exerts multiple effects on immune cells, as well as having functions outside the immune system. MIF can promote inflammation through the induction of other cytokines, including TNF, IL-6, and IL-1 family cytokines. Here, we show that inhibition of MIF regulates the release of IL-1α, IL-1β, and IL-18, not...
Alternative Titles
Full title
Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e3f4f9c8a1b94be9979682bf263d2d83
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e3f4f9c8a1b94be9979682bf263d2d83
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-04581-2
