Cryo-EM structure and oligomerization of the human planar cell polarity core protein Vangl1
Cryo-EM structure and oligomerization of the human planar cell polarity core protein Vangl1
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Author / Creator
Zhang, Fan , Li, Shaobai , Wu, Hao and Chen, Shanshuang
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Vangl is a planar cell polarity (PCP) core protein essential for aligned cell orientation along the epithelial plane perpendicular to the apical-basal direction, which is important for tissue morphogenesis, development and collective cell behavior. Mutations in Vangl are associated with developmental defects, including neural tube defects (NTDs), a...
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Full title
Cryo-EM structure and oligomerization of the human planar cell polarity core protein Vangl1
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TN_cdi_doaj_primary_oai_doaj_org_article_e42bfd4445844fab80b71f9010dd8a7d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e42bfd4445844fab80b71f9010dd8a7d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-55397-2
