Thiazole Functionalization of Thiosemicarbazone for Cu(II) Complexation: Moving toward Highly Effici...
Thiazole Functionalization of Thiosemicarbazone for Cu(II) Complexation: Moving toward Highly Efficient Anticancer Drugs with Promising Oral Bioavailability
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
In this work, we report the synthesis of a new thiosemicarbazone-based drug of N'-(di(pyridin-2-yl)methylene)-4-(thiazol-2-yl)piperazine-1-carbothiohydrazide (H
) featuring a thiazole spectator for efficient coordination with Cu(II) to give [CuCl(
)]
(
) and [Cu(NO
)(
)]
(
). Both
and
exhibit dimeric structures ascribe...
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Full title
Thiazole Functionalization of Thiosemicarbazone for Cu(II) Complexation: Moving toward Highly Efficient Anticancer Drugs with Promising Oral Bioavailability
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TN_cdi_doaj_primary_oai_doaj_org_article_e432b6901661456e9a1d22784e954d7f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e432b6901661456e9a1d22784e954d7f
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules29163832
