Personal model‐assisted identification of NAD+ and glutathione metabolism as intervention target in...
Personal model‐assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD
About this item
Full title
Author / Creator
Mardinoglu, Adil , Bjornson, Elias , Zhang, Cheng , Klevstig, Martina , Söderlund, Sanni , Ståhlman, Marcus , Adiels, Martin , Hakkarainen, Antti , Lundbom, Nina , Kilicarslan, Murat , Hallström, Björn M , Lundbom, Jesper , Vergès, Bruno , Barrett, Peter Hugh R , Watts, Gerald F , Serlie, Mireille J , Nielsen, Jens , Uhlén, Mathias , Smith, Ulf , Marschall, Hanns‐Ulrich , Taskinen, Marja‐Riitta and Boren, Jan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
To elucidate the molecular mechanisms underlying non‐alcoholic fatty liver disease (NAFLD), we recruited 86 subjects with varying degrees of hepatic steatosis (HS). We obtained experimental data on lipoprotein fluxes and used these individual measurements as personalized constraints of a hepatocyte genome‐scale metabolic model to investigate metabo...
Alternative Titles
Full title
Personal model‐assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD
Authors, Artists and Contributors
Author / Creator
Bjornson, Elias
Zhang, Cheng
Klevstig, Martina
Söderlund, Sanni
Ståhlman, Marcus
Adiels, Martin
Hakkarainen, Antti
Lundbom, Nina
Kilicarslan, Murat
Hallström, Björn M
Lundbom, Jesper
Vergès, Bruno
Barrett, Peter Hugh R
Watts, Gerald F
Serlie, Mireille J
Nielsen, Jens
Uhlén, Mathias
Smith, Ulf
Marschall, Hanns‐Ulrich
Taskinen, Marja‐Riitta
Boren, Jan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e43610ba34b24032ab9bcfbc35617cd8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e43610ba34b24032ab9bcfbc35617cd8
Other Identifiers
ISSN
1744-4292
E-ISSN
1744-4292
DOI
10.15252/msb.20167422
