Targeted inhibition of PTPN22 is a novel approach to alleviate osteogenic responses in aortic valve...
Targeted inhibition of PTPN22 is a novel approach to alleviate osteogenic responses in aortic valve interstitial cells and aortic valve lesions in mice
About this item
Full title
Author / Creator
Li, Shunyi , Luo, Zichao , Su, Shuwen , Wen, Liming , Xian, Gaopeng , Zhao, Jing , Xu, Xingbo , Xu, Dingli and Zeng, Qingchun
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
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Scope and Contents
Contents
Calcific aortic valve disease (CAVD) is the most prevalent valvular disease and has high morbidity and mortality. CAVD is characterized by complex pathophysiological processes, including inflammation-induced osteoblastic differentiation in aortic valve interstitial cells (AVICs). Novel anti-CAVD agents are urgently needed. Protein tyrosine phosphat...
Alternative Titles
Full title
Targeted inhibition of PTPN22 is a novel approach to alleviate osteogenic responses in aortic valve interstitial cells and aortic valve lesions in mice
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e44980ca86af4361a12bb1939a5808fa
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e44980ca86af4361a12bb1939a5808fa
Other Identifiers
ISSN
1741-7015
E-ISSN
1741-7015
DOI
10.1186/s12916-023-02888-6
