Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Dro...
Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance
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England: BioMed Central Ltd
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English
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Publisher
England: BioMed Central Ltd
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Insulin and insulin-like growth factors (IGFs) signal through a highly conserved pathway and control growth and metabolism in both vertebrates and invertebrates. In mammals, insulin-like growth factor binding proteins (IGFBPs) bind IGFs with high affinity and modulate their mitogenic, anti-apoptotic and metabolic actions, but no functional homologs...
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Full title
Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance
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TN_cdi_doaj_primary_oai_doaj_org_article_e47e9a6d0d4b456fa0d76a22ef37b940
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e47e9a6d0d4b456fa0d76a22ef37b940
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ISSN
1475-4924,1478-5854
E-ISSN
1475-4924
DOI
10.1186/jbiol72
