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Treacle's ability to form liquid-like phase condensates is essential for nucleolar fibrillar center...

Treacle's ability to form liquid-like phase condensates is essential for nucleolar fibrillar center...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e49768d057144f149ac9b9bd1df06e89

Treacle's ability to form liquid-like phase condensates is essential for nucleolar fibrillar center assembly, efficient rRNA transcription and processing, and rRNA gene repair

About this item

Full title

Treacle's ability to form liquid-like phase condensates is essential for nucleolar fibrillar center assembly, efficient rRNA transcription and processing, and rRNA gene repair

Publisher

England: eLife Sciences Publications, Ltd

Journal title

eLife, 2025-04, Vol.13

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications, Ltd

More information

Scope and Contents

Contents

We investigated the role of the nucleolar protein Treacle in organizing and regulating the nucleolus in human cells. Our results support Treacle's ability to form liquid-like phase condensates through electrostatic interactions among molecules. The formation of these biomolecular condensates is crucial for segregating nucleolar fibrillar centers fr...

Alternative Titles

Full title

Treacle's ability to form liquid-like phase condensates is essential for nucleolar fibrillar center assembly, efficient rRNA transcription and processing, and rRNA gene repair

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e49768d057144f149ac9b9bd1df06e89

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e49768d057144f149ac9b9bd1df06e89

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.96722

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