Treacle's ability to form liquid-like phase condensates is essential for nucleolar fibrillar center...
Treacle's ability to form liquid-like phase condensates is essential for nucleolar fibrillar center assembly, efficient rRNA transcription and processing, and rRNA gene repair
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England: eLife Sciences Publications, Ltd
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English
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England: eLife Sciences Publications, Ltd
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We investigated the role of the nucleolar protein Treacle in organizing and regulating the nucleolus in human cells. Our results support Treacle's ability to form liquid-like phase condensates through electrostatic interactions among molecules. The formation of these biomolecular condensates is crucial for segregating nucleolar fibrillar centers fr...
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Treacle's ability to form liquid-like phase condensates is essential for nucleolar fibrillar center assembly, efficient rRNA transcription and processing, and rRNA gene repair
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TN_cdi_doaj_primary_oai_doaj_org_article_e49768d057144f149ac9b9bd1df06e89
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e49768d057144f149ac9b9bd1df06e89
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2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.96722