MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution
MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Aneuploidy, chromosomal instability, somatic copy-number alterations, and whole-genome doubling (WGD) play key roles in cancer evolution and provide information for the complex task of phylogenetic inference. We present MEDICC2, a method for inferring evolutionary trees and WGD using haplotype-specific somatic copy-number alterations from single-ce...
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Full title
MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution
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TN_cdi_doaj_primary_oai_doaj_org_article_e4b330fa56874857bbfdc7ede9300d31
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e4b330fa56874857bbfdc7ede9300d31
Other Identifiers
ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-022-02794-9
