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SGLT2 inhibition improves coronary flow velocity reserve and contractility: role of glucagon signali...

SGLT2 inhibition improves coronary flow velocity reserve and contractility: role of glucagon signali...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e4b485641d78496b9714711ae24f8c10

SGLT2 inhibition improves coronary flow velocity reserve and contractility: role of glucagon signaling

About this item

Full title

SGLT2 inhibition improves coronary flow velocity reserve and contractility: role of glucagon signaling

Publisher

England: BioMed Central Ltd

Journal title

Cardiovascular Diabetology, 2024-11, Vol.23 (1), p.408-15, Article 408

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

SGLT2 inhibitors, a T2DM medication to lower blood glucose, markedly improve cardiovascular outcomes but the underlying mechanism(s) are not fully understood. SGLT2i's produce a unique metabolic pattern by lowering blood glucose without increasing insulin while increasing ketone body and glucagon levels and reducing body weight. We tested if glucag...

Alternative Titles

Full title

SGLT2 inhibition improves coronary flow velocity reserve and contractility: role of glucagon signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e4b485641d78496b9714711ae24f8c10

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e4b485641d78496b9714711ae24f8c10

Other Identifiers

ISSN

1475-2840

E-ISSN

1475-2840

DOI

10.1186/s12933-024-02491-w

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