PAX7 target genes are globally repressed in facioscapulohumeral muscular dystrophy skeletal muscle
PAX7 target genes are globally repressed in facioscapulohumeral muscular dystrophy skeletal muscle
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Facioscapulohumeral muscular dystrophy (FSHD) is a prevalent, incurable myopathy, linked to hypomethylation of
D4Z4
repeats on chromosome 4q causing expression of the DUX4 transcription factor. However, DUX4 is difficult to detect in FSHD muscle biopsies and it is debatable how robust changes in DUX4 target gene expression are as an FSHD biom...
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Full title
PAX7 target genes are globally repressed in facioscapulohumeral muscular dystrophy skeletal muscle
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TN_cdi_doaj_primary_oai_doaj_org_article_e4c41a2342de44989834fb0cef7eaaf9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e4c41a2342de44989834fb0cef7eaaf9
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01200-4
