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In silico docking and comparative ADMET profile of different glycogen synthase kinase 3 beta inhibit...

In silico docking and comparative ADMET profile of different glycogen synthase kinase 3 beta inhibit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e4c4b27ebcea40d7943279a08faa033e

In silico docking and comparative ADMET profile of different glycogen synthase kinase 3 beta inhibitors as the potential leads for the development of anti-Alzheimer drug therapy

About this item

Full title

In silico docking and comparative ADMET profile of different glycogen synthase kinase 3 beta inhibitors as the potential leads for the development of anti-Alzheimer drug therapy

Publisher

India: Wolters Kluwer India Pvt. Ltd

Journal title

Journal of advanced pharmaceutical technology and research, 2020-10, Vol.11 (4), p.194-201

Language

English

Formats

Publication information

Publisher

India: Wolters Kluwer India Pvt. Ltd

More information

Scope and Contents

Contents

Glycogen synthase kinase 3 beta (GSK3 β) plays a key role in pathologic hyper phosphorylation of tau and plays an important role in the pathogenesis of Alzheimer's disease. In the present study, we have screened a set of potential hits in in silico platform to gain insight regarding binding profile with the target (GSK3 β) from molecular docking, A...

Alternative Titles

Full title

In silico docking and comparative ADMET profile of different glycogen synthase kinase 3 beta inhibitors as the potential leads for the development of anti-Alzheimer drug therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e4c4b27ebcea40d7943279a08faa033e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e4c4b27ebcea40d7943279a08faa033e

Other Identifiers

ISSN

2231-4040

E-ISSN

0976-2094

DOI

10.4103/japtr.JAPTR_178_19

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