Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin dr...
Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Single drug use has not achieved satisfactory results in the treatment of prostate cancer, despite application of increasingly widespread targeted therapeutics. In the present study, the combined impact of the mammalian target of rapamycin (mTOR)-inhibitor RAD001, the dual EGFr and VGEFr tyrosine kinase inhibitor AEE788 and the histone deacetylase...
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Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis
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TN_cdi_doaj_primary_oai_doaj_org_article_e4deca6da4dc4ce2a0267bfa67dc932b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e4deca6da4dc4ce2a0267bfa67dc932b
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/1471-2407-11-375
