In vitro alternative for reactogenicity assessment of outer membrane vesicle based vaccines
In vitro alternative for reactogenicity assessment of outer membrane vesicle based vaccines
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Intrinsic or added immune activating molecules are key for most vaccines to provide desired immunity profiles but may increase systemic reactogenicity. Regulatory agencies require rabbit pyrogen testing (RPT) for demonstration of vaccine reactogenicity. Recently, the monocyte activation test (MAT) gained popularity as in vitro alternative, yet this...
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In vitro alternative for reactogenicity assessment of outer membrane vesicle based vaccines
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TN_cdi_doaj_primary_oai_doaj_org_article_e4e7d7d3c4fe4e64adcffc572b4ed1ec
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e4e7d7d3c4fe4e64adcffc572b4ed1ec
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-39908-7