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An auto-inhibited state of protein kinase G and implications for selective activation

An auto-inhibited state of protein kinase G and implications for selective activation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e51c69fdbce043f9a7cfb5d14e739a4b

An auto-inhibited state of protein kinase G and implications for selective activation

About this item

Full title

An auto-inhibited state of protein kinase G and implications for selective activation

Publisher

United States: eLife Sciences Publications, Ltd

Journal title

eLife, 2022-08, Vol.11

Language

English

Formats

Publication information

Publisher

United States: eLife Sciences Publications, Ltd

More information

Scope and Contents

Contents

Cyclic GMP-dependent protein kinases (PKGs) are key mediators of the nitric oxide/cyclic guanosine monophosphate (cGMP) signaling pathway that regulates biological functions as diverse as smooth muscle contraction, cardiac function, and axon guidance. Understanding how cGMP differentially triggers mammalian PKG isoforms could lead to new therapeuti...

Alternative Titles

Full title

An auto-inhibited state of protein kinase G and implications for selective activation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e51c69fdbce043f9a7cfb5d14e739a4b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e51c69fdbce043f9a7cfb5d14e739a4b

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.79530

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