Deoxycytidine kinase inactivation enhances gemcitabine resistance and sensitizes mitochondrial metab...
Deoxycytidine kinase inactivation enhances gemcitabine resistance and sensitizes mitochondrial metabolism interference in pancreatic cancer
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Pancreatic ductal adenocarcinoma (PDAC) is considered one of the most lethal forms of cancer. Although in the last decade, an increase in 5-year patient survival has been observed, the mortality rate remains high. As a first-line treatment for PDAC, gemcitabine alone or in combination (gemcitabine plus paclitaxel) has been used; however, drug resis...
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Deoxycytidine kinase inactivation enhances gemcitabine resistance and sensitizes mitochondrial metabolism interference in pancreatic cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_e52b92cb32444e7285c5deb3aaca81cd
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e52b92cb32444e7285c5deb3aaca81cd
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-024-06531-x
